Curcumin is a dye obtained by extraction from turmeric (Curcuma Longa L}. Derivatives of curcumin have been synthesized, mainly involving additions at the carbon between the two carbonyl groups. This research attempted to add an indole at both positions β to the ketone carbonyls to form 1,7-bis(indolyl)curcumin. The catalyst free, "on-water" synthesis was implemented and the resulting solid analyzed. A three step synthesis was then executed which involved the formation of an acylindole derivative and its subsequent reaction with a diketone to produce the desired product.
Kisunzu, Jessica, "Investigation into the Synthesis of Turmeric Derivatives" (2008). Senior Research Projects. 22.