Hyperbaric oxygen therapy promotes faster tissue healing by increasing the amount of oxygen carried to the tissues. HBO is currently used to treat carbon monoxide poisoning as well as smoke inhalation. Based on this information, it was believed that HBO would also promote faster healing for hydrogen cyanide gas or hydrogen chloride gas inhalation, which are encountered in burning material. To test this theory, mice were exposed to HCN or HCl gas. The mice were then placed in hyperbaric oxygen or supplemental oxygen treatments for five days. Weight change and overall survival rate were used to establish what method of treatment was ideal. It was determined that mice treated with supplemental oxygen healed as quickly as those treated with hyperbaric oxygen. Therefore, in the case of hydrogen cyanide or hydrogen chloride inhalation, supplemental oxygen is the better treatment.
Rader, Renee; Rader, Russell; and Wunderlich, Daniel, "Treatment of Hydrogen Cyanide and Hydrogen Chloride Inhalation in Mice with Hyperbaric Oxygen Therapy versus Supplemental Oxygen" (2002). Senior Research Projects. 66.