Some invertebrate and vertebrate species have the ability to regenerate a lost limb. The lizard species are unique in that they can autotomize their tails and regrow them back. In this study, the proteomic change occurring within the regenerating tail of Anolis carolinensis (Green anole) during 72 h period was examined. We ran 2-dimension electrophoresis to separate the proteins and utilized SameSpots software to find 6 different spots that had altered expression of protein. Within those spots, proteins involved in immunity, energetics, and protein folding and degradation were identified. The proteins that were up-regulated were transferrin, nucleotide-binding domain of the sugar kinase superfamily, and CH1 domain in immunoglobulin. The down-regulated proteins include T-complex protein 1, phosphoglucomutase 1, AAA, creatine kinase, ESP15 homology domain, and PINT motif.
Hong, Victor and Thornton, Benjamin, "Differential Protein Expression During Tail Regeneration of Anolis carolinensis" (2015). Research in Biology. 3.