A Novel Method for the Synthesis of Phosphindolizine.

Presenter Information

Brandon EdelbachFollow

Presentation Type

Oral Presentation

Mentor/Supervising Professor Name

Dr. Matthew Duffy

Description

The purpose of this experimental design is to devise a novel method for the synthesis of phosphindolizine. The proposed mechanism includes the synthesis of 3,4-dimethyl – 2Hphospole, and 3,4-dimethyl-1-phenyl-, 1-sulfide. These two products will be reacted together via a 2+4 Diels alder reaction to create a 7-phosphanorbornene, and the phosphorous groups in the compound will be protected by adding sulfur (S8). The bicyclic portion of this ring will then be removed via UV light in a retro-Diels Alder reaction. Following the removal of the sulfur protecting group, this represents the proposed mechanism for synthesizing phosphindolizine.

This document is currently not available here.

Share

COinS
 
Apr 21st, 8:00 AM Apr 21st, 10:00 AM

A Novel Method for the Synthesis of Phosphindolizine.

The purpose of this experimental design is to devise a novel method for the synthesis of phosphindolizine. The proposed mechanism includes the synthesis of 3,4-dimethyl – 2Hphospole, and 3,4-dimethyl-1-phenyl-, 1-sulfide. These two products will be reacted together via a 2+4 Diels alder reaction to create a 7-phosphanorbornene, and the phosphorous groups in the compound will be protected by adding sulfur (S8). The bicyclic portion of this ring will then be removed via UV light in a retro-Diels Alder reaction. Following the removal of the sulfur protecting group, this represents the proposed mechanism for synthesizing phosphindolizine.